Selenium is a structural component of an essential enzyme system- glutathione peroxidase, and functions in association with vitamin E, certain fats and sulfur amino acids. Selenium has also been recognized as an immune-stimulant in ruminants. Selenium, via GSHpx, is involved with metabolism of arachadonic acid to prostaglandins. Supplementation of selenium improves the killing ability of neutrophils improve immune system.

Deficiencies result in white muscle disease in young calves, cardiac and skeletal muscle degeneration, heart failure, and paralysis of the hind legs. Other problems that have responded to supplementation of selenium include metritis, cystic ovaries and udder oedema. A reduction in retained placentas may occur when cattle are treated with injectable selenium and Vitamin E.

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All Telsol's glass boluses contain cobalt, copper and selenium with either iodine or zinc.
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